Recurrent and novel evolutionary pathways drive in vitro HIV-1 lenacapavir resistance with diverse phenotypic consequences.

Nat Commun · 2026 · PMC13096457 · PMID 41794817

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did not reach statistical significanceno p-value reported

Single-round infectivity was comparable between Q67H and Q67N, while Q67H showed a modest trend toward higher replicative capacity relative to Q67N that did not reach statistical significance.

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