Impact of early dexmedetomidine administration on short- and long-term outcomes in critically traumatic brain injury patients: A retrospective study using the MIMIC-IV database.

Ibrain · 2026 · PMC13097420 · PMID 42023254

Europe PMC DOI

hedged sentence

0.1000

closest p · 2.0× alpha

0.1000

boldest claim

The sentences

did not reach statistical significancep < 0.1so close (0.05 < p ≤ 0.1)

Although tests for interaction did not reach statistical significance (0.05 < p < 0.1), the substantial reduction in hazard ratios within these specific subgroups warrants mechanistic consideration.

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