Host-specific functional evolution of seal influenza A virus NS1 protein following avian-to-seal transmission.

J Virol · 2026 · PMC13098261 · PMID 41874045

Europe PMC DOI

hedged sentence

0.0590

closest p · 1.2× alpha

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The sentences

failed to reach statistical significanceP < 0.059so close (0.05 < p ≤ 0.1)

The results were striking: the T94I substitution alone significantly increased NS1 expression in avian and human cells ( P < 0.01), and a similar trend was observed in seal cells, although it failed to reach statistical significance ( P < 0.059).

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