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IL-18-armed oncolytic vaccinia virus remodels the suppressive microenvironment via macrophage and Treg modulation in lymphoma.

Cancer Immunol Immunother · 2026 · PMC13100099 · PMID 42012649

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Comparative analysis demonstrated that, relative to the PBS-treated control group, OVV treatment resulted in a modest reduction in tumor growth rate; however, this difference did not reach statistical significance (Fig. 1 B).

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