Surface CD81 supports leukemia stem cell function and reveals a therapeutic vulnerability in acute myeloid leukemia.

Signal Transduct Target Ther · 2026 · PMC13100155 · PMID 42014680

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did not reach statistical significanceno p-value reported

35 , 36 Of note, AML with NPM1 mutation showed lower CD81 expression, although this did not reach statistical significance; therefore for this subset only, we applied a lower cut-off to define high CD81 in this study.

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