Oxidative stress causes a reversible decrease of deubiquitylases activity in old vertebrate brains.

Nat Commun · 2026 · PMC13100221 · PMID 42014687

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showed a trendno p-value reported

While total ubiquitylated protein levels showed a trend toward decreased accumulation, K48-linked polyubiquitylated protein levels were significantly reduced in NACET-treated brains (Fig. 5D , Fig.

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