Sex-based antibody subclass maturation drives direct enzymatic inhibition in fabry disease patients receiving enzyme replacement therapy.

Front Mol Biosci · 2026 · PMC13102577 · PMID 42037649

Europe PMC DOI

hedged sentence

0.1100

closest p · 2.2× alpha

0.1100

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The sentences

did not reach statistical significancep = 0.11not close (p > 0.1)

Additionally, IgG4 binding was associated with elevated plasma lyso-Gb3 levels, however this did not reach statistical significance ( Figure 4D ; p = 0.11).

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