The Italian Assessment System for Innovative Medicines: An 8-Year Retrospective Analysis of Outcomes, Criteria, Timelines and Funding Dynamics.

Appl Health Econ Health Policy · 2026 · PMC13102879 · PMID 41781747

Europe PMC DOI

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a decreasing trendno p-value reported

From 2017 to 2023, a decreasing trend in the percentage of “Full Innovative” assessments was observed (slope = −5.96), but it was not statistically significant ( p = 0.62), suggesting year-to-year fluctuations rather than a consistent pattern.

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did not reach statistical significanceno p-value reported

Other variables, including TN, oncologic indication, and ATMP status, did not reach statistical significance.

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