In drug-sensitive NCI-H460 cells, the GI 50 of paclitaxel or vinorelbine combined with bosutinib [ Figure 3A and B ] was lower than that of each drug alone, although the differences did not reach statistical significance.
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Extracellular vesicles shed by multidrug resistant cells contribute to the identification of SRC inhibitors as chemosensitizers in non-small cell lung cancer.
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