New indole-linked 1,2,4-triazole derivatives as dual FAK inhibitors and apoptosis inducers targeting survival and migration in triple-negative breast cancer in-vitro.

As well, compound 3c treatment significantly decreased FAK levels to 29.33 ± 1.13 ng/mL (50.4% inhibition), while compound 2 caused a moderately significant reduction, resulting in a FAK concentration of 41.31 ± 1.60 ng/mL (30.1% inhibition) (Fig. 7 , Table 2 ).

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