Frailty status and the risk of dementia, Alzheimer's disease: a meta-analysis of observational studies.

Front Neurol · 2026 · PMC13106089 · PMID 42037682

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did not reach statistical significanceno p-value reported

For Alzheimer’s disease, the pooled estimate suggested increased odds but did not reach statistical significance (OR = 1.91, 95% CI: 0.86–4.20), and the evidence was limited by the small number of contributing studies (k = 4) and substantial heterogeneity.

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