In the HSCT cohort, five-year OS was 100% in PNH-positive patients and 90% in PNH-negative patients; however, this difference did not reach statistical significance (100% vs. 90%; p = 0.09) (Fig. 2 ).
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Prognostic significance of PNH clones in aplastic anemia treated with immunosuppression or allogeneic HSCT: a 20-year single-center experience.
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Although this difference did not reach statistical significance, a numerical trend toward improved outcomes in PNH-positive patients was observed.