Single cell transcriptional evolution of myeloid leukemia of Down syndrome.

Nat Commun · 2026 · PMC13106683 · PMID 42026063

Europe PMC DOI

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0.0550

closest p · 1.1× alpha

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The sentences

near-significantp = 0.055so close (0.05 < p ≤ 0.1)

Although limited by small sample size, ML-DS enrichment scores were higher in progressive compared to conventional TAM samples, with a near-significant difference (one-sided t-test, p = 0.055), supporting the notion that the ML-DS transcriptomes may help delineate TAM cases at higher risk of progression.

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