Barely Significant
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Cancer IDO1-Mediated Tryptophan-Kynurenine Metabolic Reprogramming to Drive Skeletal Muscle Atrophy and Cachexia Acceleration.

J Cachexia Sarcopenia Muscle · 2026 · PMC13107547 · PMID 42028912

Europe PMCDOI
1
hedged sentence
0.0010
closest p · 0.0× alpha
0.0010
boldest claim

The sentences

a marked trendp < 0.001actually significant
Notably, the Ido1‐KO group exhibited a marked trend towards restored p‐4EBP1 ( p < 0.001) and p‐P70S6K ( p < 0.001) levels, suggesting that Ido1 KO helped maintain anabolic signalling pathways under tumour burden (Figure 3A–D ).

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