Longitudinal immune cell dynamics and heterogeneous trajectories in children with scrub typhus: a descriptive pilot study.

BMC Pediatr · 2026 · PMC13107700 · PMID 41845335

Europe PMC DOI

hedged sentences

0.0780

closest p · 1.6× alpha

0.0780

boldest claim

The sentences

a positive trendP = 0.078so close (0.05 < p ≤ 0.1)

Days after fever onset showed no significant effect on CD4/CD8 ratio (β = -0.34, 95% CI: -0.79 to 0.12, P = 0.144), while days of treatment showed a positive trend with CD4/CD8 ratio (β = 0.59, 95% CI: -0.07 to 1.24, P = 0.078).

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did not reach statistical significanceP = 0.078so close (0.05 < p ≤ 0.1)

Days of treatment showed a positive trend with the CD4/CD8 ratio, but this did not reach statistical significance (β = 0.59, 95% CI: -0.07 to 1.24, P = 0.078), suggesting a potential recovery tendency of the ratio after effective treatment, which requires further validation with an expanded sample size (Fig. 2 , Table 2 ).

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