High uPAR and Low miR-221 Expression Predict Poor Disease-Free Survival in Triple-Negative Breast Cancer.

Pathophysiology · 2026 · PMC13108178 · PMID 42029556

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hedged sentences

0.0600

closest p · 1.2× alpha

0.0600

boldest claim

The sentences

showed a trendp = 0.060so close (0.05 < p ≤ 0.1)

In contrast, elevated uPAR mRNA expression was significantly associated with shorter DFS (HR: 2.24; 95% CI: 1.15–4.35; p = 0.017) and showed a trend towards reduced OS (HR: 1.95; 95% CI: 0.97–3.89; p = 0.060) in univariate Cox regression analysis ( Table 2 ).

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borderline significantno p-value reported

The same tendencies for both markers were also found, with a borderline significant association with OS.

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