Real-world efficacy of Bruton tyrosine kinase inhibitor based maintenance therapy in diffuse large B-cell lymphoma: a multicenter retrospective cohort study with external historical control.

Cancer Biol Ther · 2026 · PMC13108342 · PMID 42015349

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did not reach statistical significanceno p-value reported

Although this trend did not reach statistical significance, it implies that BTKi maintenance may be more efficacious for the MCD subtype, whereas current therapeutic strategies remain insufficient for enhancing outcomes in the A53 subtype.

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