Efficacy of GLP-1 Receptor agonists in treating Obstructive sleep apnea: A systematic review and meta-analysis of cardiometabolic and respiratory outcomes.

Sleep Breath · 2026 · PMC13109165 · PMID 42029967

Europe PMC DOI

hedged sentences

0.0600

closest p · 1.2× alpha

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boldest claim

The sentences

a trend toward significancep = 0.06so close (0.05 < p ≤ 0.1)

Similarly, among those not using CPAP, GLP-1 RAs showed a trend toward significance (MD: −1.49 mmHg; 95% CI: −2.94 to −0.05; p = 0.06, Fig. 4 .B).

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showed a trendp = 0.06so close (0.05 < p ≤ 0.1)

Similarly, among those not using CPAP, GLP-1 RAs showed a trend toward significance (MD: −1.49 mmHg; 95% CI: −2.94 to −0.05; p = 0.06, Fig. 4 .B).

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did not reach statistical significanceno p-value reported

4 A), which did not reach statistical significance, possibly due to wider confidence intervals and heterogeneity ( I2 = 94.6%).

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