Lower Prevalence of Asymptomatic Alzheimer's Disease Among Healthy African Americans.

For tTau and pTau, all pairwise comparisons showed highly significant differences ( p < 0.0001) across all groups with AA individuals showing lower levels ( Fig 1B , C ).

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Among CN controls, the coefficient for age (per decade) was marginally significant for Aβ 42 (−36.67 pg/ml, −3.0%, p < 0.05), and highly significant for tTau (+23.37 pg/ml, +13.3%, p < 0.001) and pTau (+2.06 pg/ml, +13.3%, p < 0.001).

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Vascular cognitive impairment was diagnosed more frequently in AA than white patients (14% vs 10%), but this did not reach statistical significance.

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