IL-6 triggers lysosomal degradation of LDL-R and enhances LDL-C uptake in vascular endothelial cells via macropinocytosis.

However, we found a trend towards an increase in the level of Mylip protein in ECs following stimulation with IL-6 + sIL-6R (mean difference = 0.004, p -value = 0.216) although it did not reach statistical significance (Fig. 2 D).

also in 111,027 other papers