Molecular mechanisms of insulin resistance and altered carbohydrate metabolism in PCOS: a scoping review.

Front Endocrinol (Lausanne) · 2026 · PMC13111087 · PMID 42051446

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did not reach statistical significanceno p-value reported

Although transcriptional changes in some glycolytic genes did not reach statistical significance in rat liver, the overall pattern suggests that neutrophil extracellular traps suppress hepatic glycolysis and reduce insulin responsiveness, leading to metabolic inflexibility.

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