Hyperaldosteronism in Mice Lacking the Distal Polybasic Tract of the γ-Subunit of the Epithelial Sodium Channel During Sodium Restriction.

Plasma corticosterone concentrations significantly increased in γENaC wt/wt mice under a low sodium diet and amiloride treatment, this increase was similar in γENaC ki/ki mice, however, did not reach statistical significance (Figure 2F ). 3.3.

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