The effects of metformin and exercise training on cardiorespiratory, blood pressure, and metabolic adaptations across the spectrum of glucose dysregulation: a systematic review and meta-analysis.

When applying a multilevel model to adjust for dependence between subgroups within the same study, the effect remained in the same direction, although it did not reach statistical significance (MD = −1.180; 95% CI −3.813 to 1.454; I 2 = 0.00%; p = 0.170; Figure S6 ).

also in 111,027 other papers