Research Progress of PROTACs in Breast Cancer: Subtype-Oriented Target Landscape, Clinical Stratification Evidence, and Engineering Strategies for Translation.

Biomedicines · 2026 · PMC13113217 · PMID 42072376

Europe PMC DOI

hedged sentence

0.0700

closest p · 1.4× alpha

0.0700

boldest claim

The sentences

did not reach statistical significancep = 0.07so close (0.05 < p ≤ 0.1)

In the overall intent-to-treat (ITT) population, the PFS difference was smaller and did not reach statistical significance (3.8 months vs. 3.6 months; HR, 0.83; p = 0.07).

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