Combined Transcriptomic and Proteomic Profiling Uncovers Developmental Dynamics of Autophagy in the Cortex.

For instance, clusters 1 and 2 showed a trend of low expression at E16, which increased progressively at P5 and P10, indicating that these autophagy-related genes become more active during postnatal brain development, probably contributing to processes such as circuit maturation, neuronal connectivity, and synaptic plasticity.

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