Distinct Molecular Responses to Ketamine and Imipramine in Cortical and Striatal Regions Following Acute Swim Stress.

Biomolecules · 2026 · PMC13114071 · PMID 42072607

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closest p

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highly significantno p-value reported

The FST × Gene interaction (F(4, 403.6) = 42.05, p < 0.001, η 2 p = 0.287) and the Gene × Region interaction (F(8, 404.4) = 22.75, p < 0.001, η 2 p = 0.304) were also highly significant, reflecting that stress effects and regional expression patterns varied across genes.

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did not reach statistical significanceno p-value reported

While imipramine significantly reduced total immobility time, ketamine produced a smaller effect that did not reach statistical significance.

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