Gene-Specific Outcomes After Central Nervous System Metastases in Germline BRCA1- and BRCA2-Associated Breast Cancer.

Multivariate Analysis In a multivariable model stratified by subtype (n = 77, restricted to luminal and triple-negative subtype, Table 2 ), g BRCA2 PV carriers had a lower hazard of death compared with non-carriers (HR = 0.48, 95% CI 0.18–1.25, p = 0.131), although this finding did not reach statistical significance. g BRCA1 PV carriers had hazards like non-carriers (HR 0.90, 95% CI 0.49–1.64, p = 0.730).

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