Hyperthermia Combined with Anti-CTLA-4 Antibody Induces Tumor Microenvironment Remodeling Involving CD4<sup>+</sup> T Cells in Local and Distant Antitumor Effects in a Murine Triple-Negative Breast Cancer.

Cancers (Basel) · 2026 · PMC13114660 · PMID 42073618

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did not reach statistical significanceno p-value reported

Although the proportion of CTL appeared higher in the HT + C4 group than in the C4 group, the difference did not reach statistical significance ( Figure 3 A,B).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.

Hyperthermia Combined with Anti-CTLA-4 Antibody Induces Tumor Microenvironment Remodeling Involving CD4&lt;sup&gt;+&lt;/sup&gt; T Cells in Local and Distant Antitumor Effects in a Murine Triple-Negative Breast Cancer.

The sentences

Hyperthermia Combined with Anti-CTLA-4 Antibody Induces Tumor Microenvironment Remodeling Involving CD4<sup>+</sup> T Cells in Local and Distant Antitumor Effects in a Murine Triple-Negative Breast Cancer.