Different <i>SF3B1</i> Mutation Hotspots Show Hematopoietic Lineage-Specific VAF Patterns and Correlate with Distinct Genetic and Prognostic Profiles in Patients with Myeloid Neoplasms.

Cancers (Basel) · 2026 · PMC13114748 · PMID 42073631

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did not reach statistical significanceno p-value reported

There was a trend toward younger age at diagnosis among patients with multilineage SF3B1 mutations (mean age 65.8 years) compared to patients with BM-restricted mutations (mean age 70.4 years), but the difference did not reach statistical significance.

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Different &lt;i&gt;SF3B1&lt;/i&gt; Mutation Hotspots Show Hematopoietic Lineage-Specific VAF Patterns and Correlate with Distinct Genetic and Prognostic Profiles in Patients with Myeloid Neoplasms.

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Different <i>SF3B1</i> Mutation Hotspots Show Hematopoietic Lineage-Specific VAF Patterns and Correlate with Distinct Genetic and Prognostic Profiles in Patients with Myeloid Neoplasms.