highly significantp < 0.001
These reductions were highly significant ( p < 0.001) with very large effect sizes (Cohen’s d > 2).
These reductions were highly significant ( p < 0.001) with very large effect sizes (Cohen’s d > 2).
Regarding pulmonary metrics, hypofractionation was also associated with greater reductions in the mean lung dose, while the association with lung V20 showed a similar trend but did not reach statistical significance in multivariable analysis.