Barely Significant
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Serum Trimethylamine-<i>N</i>-Oxide and Its Precursors as a Diagnostic Biomarker Panel for Non-Muscle-Invasive Bladder Cancer.

Int J Mol Sci · 2026 · PMC13115581 · PMID 42074229

Europe PMCDOI
3
hedged sentences
0.0001
closest p · 0.0× alpha
0.7120
boldest claim

The sentences

highly significantp < 0.0001actually significant
Fisher’s exact test confirmed highly significant discrimination between patients with early-stage bladder cancer and controls ( p < 0.0001), and the corresponding OR indicated a markedly increased risk of bladder cancer above the cutoff (OR = 53.813, 95% CI 15.167–239.482).

also in 132,142 other papers

a nonsignificant trendp ≥ 0.05actually significant
Serum TMAO, carnitine, and choline levels were significantly higher in patients with NMIBC than in controls ( p ≤ 0.0001), whereas betaine showed a nonsignificant trend toward higher levels ( p ≥ 0.05).

also in 5,406 other papers

did not reach statistical significancep = 0.712not close (p > 0.1)
Betaine did not reach statistical significance (β = −0.014, OR = 0.986, 95% CI 0.915–1.062, p = 0.712).

also in 111,027 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.