From Luminal to Triple Negative: 3D Spheroids Reveal Molecular and Phenotypic Differences Across Breast Cancer Subtypes.

Although this difference did not reach statistical significance, likely due to the limited number of cell lines analyzed, the results support our observation that epithelial-like cell lines preferentially form compact spheroids, while mesenchymal-like cell lines are associated with loosely adherent spheroid structures ( Figure S6 ). 3.

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