TLC-Derived High-Polar Fractions of <i>Celastrus paniculatus</i> Seeds Attenuate Astrocyte-Driven Microglial Activation Through Suppression of CD40/iNOS Signaling and Pro-Inflammatory Cytokines.

Int J Mol Sci · 2026 · PMC13116680 · PMID 42074191

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did not reach statistical significanceno p-value reported

Co-treatment with CP fraction F7 significantly suppressed ACM-H-induced iNOS expression, while fraction F6 produced a partial reduction that did not reach statistical significance.

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TLC-Derived High-Polar Fractions of &lt;i&gt;Celastrus paniculatus&lt;/i&gt; Seeds Attenuate Astrocyte-Driven Microglial Activation Through Suppression of CD40/iNOS Signaling and Pro-Inflammatory Cytokines.

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TLC-Derived High-Polar Fractions of <i>Celastrus paniculatus</i> Seeds Attenuate Astrocyte-Driven Microglial Activation Through Suppression of CD40/iNOS Signaling and Pro-Inflammatory Cytokines.