Exploratory Multi-Level Analysis of the HIF Axis in Clear-Cell Renal Cell Carcinoma and Evaluation of GN44028 as an Experimental HIF Pathway-Modulating Compound.

Int J Mol Sci · 2026 · PMC13116724 · PMID 42074150

Europe PMC DOI

hedged sentence

0.0700

closest p · 1.4× alpha

0.0700

boldest claim

The sentences

a strong trendp = 0.070so close (0.05 < p ≤ 0.1)

4/12 in stage I + II; p = 0.007) and showed a strong trend toward higher ISUP grade (3 + 4:21/28 vs. 5/12 in 1 + 2; p = 0.070).

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