Although adjuvant treatment with tegafur–uracil (UFT) appeared to be associated with an approximately 5% improvement in 5-year recurrence rates in BD2 and BD3 tumors, these differences did not reach statistical significance.
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Tumor Budding in Colorectal Carcinoma-From Incidental Observation to Prognostic Marker: Lessons Learned from Colorectal Cancer Assessment.
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