Hemorrhagic Fever Disease in STAT-1 Knockout Mice Infected with Lujo Virus.

Pathogens · 2026 · PMC13118996 · PMID 42075721

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an interesting trendno p-value reported

Viral RNA was detected at relatively high levels in kidney, liver, and lung tissue of both STAT-1 −/− and IFrag −/− mice surviving to the planned end of the study, with an interesting trend towards the highest viral load being detected in the lung.

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showed a trendno p-value reported

Hematologic values showed a trend towards leukocytosis, anemia, and thrombocytopenia consistent with viral hemorrhagic fever disease ( Figure 2 ).

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