Increasing Transfection of Human Monocyte-Derived Dendritic Cells by Optimizing Lipid Nanoparticle Ionizable Lipid and mRNA Uridine Modification.

Pharmaceutics · 2026 · PMC13119134 · PMID 42076056

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showed a trendno p-value reported

In terms of performance ranking, our investigation in human DC showed a trend of highest to lowest ∆MFI for LNP delivery of eGFP mRNA as N1MePsU > U > 5moU.

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