Long-term outcome of isolated locoregional breast cancer recurrence: a large retrospective mono-institutional study.

Oncologist · 2026 · PMC13120875 · PMID 42011506

Europe PMC DOI

hedged sentences

0.0680

closest p · 1.4× alpha

0.0680

boldest claim

The sentences

a numerical trendP = .068so close (0.05 < p ≤ 0.1)

A numerical trend towards a lower risk of ILRR for patients receiving chemotherapy was observed (HR 0.63 95% CI 0.39-1.03; P = .068).

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showed a trendno p-value reported

Indeed, extent of nodal involvement at first BC diagnosis was significantly associated with worse DRFI (patients with N3 tumors presented a significantly worse DRFI post-ILRR as compared with those with node-negative disease: HR 5.48, 95% CI 1.16-25.95; P = .032), and patients with larger tumors at first diagnosis showed a trend towards worse DRFI post-ILRR, although not statistically significant (pT4 versus pT1: HR 7.62, 95% CI 0.94-62.02; P = .058) ( Table 3 ).

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