Immersive virtual reality as a novel approach to improve social cognition in multiple sclerosis: an EEG-based pilot study.

Clinical significance of cognitive, emotional, and social-cognitive changes Although most p-values did not reach statistical significance due to the limited sample size ( n = 7), several outcomes demonstrated changes that approached or exceeded established minimal clinically important differences (MCID) ( Draak et al., 2019 ) thereby supporting the potential clinical relevance of the observed effects ( Table 4 ).

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