We further conducted a sensitivity analysis including three CASP3 SNPs, and the results remained largely consistent with Model 2 except for CASP8 rs1045487 and CASP3 rs4647602, which showed marginal significance ( Supplementary Table 3 , only online).
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Statin-Associated Hepatotoxicity Linked to <i>CASP8</i> Polymorphisms: Mechanistic Insights from Proteomic Analysis.
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We further observed a suggestive trend toward increased CASP8 expression with the risk alleles of the three CASP8 variants.