Impaired α -Synuclein aggregate clearance in neuronal cells drive their spread to microglia through tunneling nanotubes.

Nat Commun · 2026 · PMC13121836 · PMID 41820341

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did not reach statistical significanceno p-value reported

Immunoblotting for ARP3 and its upstream regulator CDC42 showed a reduction in both proteins in neuronal cells following autophagy inhibition, although the decrease in CDC42 did not reach statistical significance.

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