Comparative Efficacy of Bulevirtide, Interferons, and Nucleos(t)ide Analogs for Chronic Hepatitis Delta: A Systematic Review and Network Meta-Analysis.

Int J Hepatol · 2026 · PMC13122728 · PMID 42057812

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did not reach statistical significanceno p-value reported

BLV, both as monotherapy (OR 1.64; 95% CI: 0.53, 5.07) and in combination with pegylated interferon alpha (OR 2.29; 95% CI: 0.56, 9.35), showed trends toward improving biochemical response, but these differences did not reach statistical significance.

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