KDM5C also exhibited female-biased expression in discovery (median log 2 FC = 0.25, FDR = 2.2 × 10 −8 ) and maintained the same sex bias in MAQC-II (log 2 FC = 0.05, 95% CI: [–0.01–0.11]), though it did not reach statistical significance (FDR = 0.72).
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Deciphering the genetic underlying causes of sex differences in multiple myeloma incidence and mortality.
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