Barely Significant
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Interaction effects of testosterone and platelet-to-lymphocyte ratio on osteoporosis in U.S. adults: Insights from the NHANES 2011 to 2016 cohort.

Medicine (Baltimore) · 2026 · PMC13124329 · PMID 42071841

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a significant trendno p-value reported
Association between PLR and osteoporosis In fully adjusted weighted logistic regression (Model 3, additionally controlling for age, sex, race/ethnicity, marital status, education, poverty-to-income ratio, smoking, alcohol use, hypertension, hyperlipidemia, diabetes, and BMI), participants in the highest PLR quartile ( Q 4) had significantly higher odds of osteoporosis than those in the lowest quartile ( Q 1) (OR = 3.58, 95% CI: 1.93–6.66; P < .001), with a significant trend across quartiles ( P for trend < .001).

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