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Beyond the interferon score: neurofilament light chain and glial fibrillary acidic protein capture immune-mediated neuroinjury and response to JAK inhibition in Aicardi-Goutières syndrome.

Front Immunol · 2026 · PMC13124696 · PMID 42064048

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Although biomarker concentrations in treated patients were lower than in untreated patients, these differences did not reach statistical significance, likely reflecting inter-individual variability and limited sample size.

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