Somatostatin receptor expression for peptide receptor radionuclide therapy in Japanese patients with recurrent or metastatic differentiated thyroid cancer.

Ann Nucl Med · 2026 · PMC13124881 · PMID 41575647

Europe PMC DOI

hedged sentences

0.0650

closest p · 1.3× alpha

0.0900

boldest claim

The sentences

a trend toward significancep = 0.065so close (0.05 < p ≤ 0.1)

showed a trendp = 0.065so close (0.05 < p ≤ 0.1)

The sensitivity analyses yielded consistent results; notably, in the GLMMs with random intercepts for patients, 131 I SUVmax tended to be positively associated with SSTR positivity (OR, 6.00, p = 0.072), while lesion size also showed a trend toward significance (OR, 1.49, p = 0.065). 18 F-FDG SUVmax was not associated with SSTR positivity ( p = 0.64).

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did not reach statistical significancep = 0.09so close (0.05 < p ≤ 0.1)

Univariate logistic regression analysis of the representative lesions (Table 4 ) revealed that only 131 I SUVmax was a predictive factor for SSTR positivity ( p = 0.037), whereas lesion size did not reach statistical significance ( p = 0.09).

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