ANCA-associated vasculitis is associated with an increased risk of cardiac and vascular morbidity: results of a large-scale propensity-matched global retrospective cohort study.

Front Immunol · 2026 · PMC13124934 · PMID 42064047

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Although not statistically significant, MPA patients showed a trend towards an increased risk of thromboembolic events (pulmonary embolism: HR 1.16, 95% CI 1.01 -1.33; deep vein thrombosis: HR 1.17, 95% CI 1.03-1.32) and the risk of heart failure compared to GPA (HR 1.15, 95% 1.03-1.27) ( Figure 3 ).

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