Cul5: immune cell function and therapeutic potential.

Front Immunol · 2026 · PMC13124974 · PMID 42064089

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did not reach statistical significanceno p-value reported

However, despite promising results in Phase I and II clinical trials, a Phase III trial for AML did not reach statistical significance in event-free survival of patients treated with pevonedistat and azacitidine versus azacitidine alone ( 139 ).

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