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Non-invasive brain stimulation for neuropathic orofacial pain: a mini-review.

Front Pain Res (Lausanne) · 2026 · PMC13125060 · PMID 42064201

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( 18 ) conducted a crossover trial in 66 patients with neuropathic pain and found that a single session of high-frequency rTMS—whether navigated to the cortical representation of the painful area or non-navigated to the hand motor hotspot—significantly reduced upper and lower limb pain, but did not reach statistical significance for facial or hemibody pain ( 19 ).

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