Barely Significant
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Functional connectivity gradients of the insula in major depressive disorder.

Front Psychiatry · 2026 · PMC13125075 · PMID 42064159

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0.1470
closest p · 2.9× alpha
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did not reach statistical significancep = 0.147not close (p > 0.1)
However, this difference in gradient range did not reach statistical significance ( t (70) = 1.465, p = 0.147). 3.4 Insula-to-seven brain networks principal gradient findings The proportions of variance explained by the insula-to-seven different brain network gradients were similar in both groups (all p s >.05, Supplementary Table 1 ).

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